Table 3. A comparison of the demographic and clinical characteristics of patients with and without secondary infection.
| Variables | Non-SI (n = 227) | SI (n = 145) | Univariate analysis |
|
|---|---|---|---|---|
| OR(CI95) | P value | |||
| Age (years) | ||||
| Median (25th, 75th) | 61 (51, 71) | 66 (58, 78) | <0.001 | |
| Age > 65 years, n(%) | 83 (36.6%) | 78 (53.8%) | 2.02 (1.32~3.09) | 0.001 |
| Male, n(%) | 124 (54.6%) | 93 (64.1%) | 1.49 (0.97~2.28) | 0.070 |
| Comorbidities | ||||
| ≥two comorbidities | 42 (18.5%) | 36 (24.8%) | 1.46 (0.88~2.41) | 0.144 |
| Admission category, n(%) | ||||
| Medical | 194 (85.5%) | 111 (75.9%) | ||
| Surgical | 33 (14.5%) | 34 (24.3%) | 1.80 (1.06~3.07) | 0.029 |
| Immunosupressive agent, n(%) | ||||
| Corticosteroid | 8 (3.5%) | 8 (5.5%) | 1.60 (0.57~4.36) | 0.355 |
| Other Immunospressive drugs | 11 (4.8%) | 6 (4.1%) | 0.85 (0.31~2.34) | 0.750 |
| alcohol abuse | 64 (28.2%) | 41 (28.3%) | 1.00 (0.63~1.60) | 0.986 |
| Site of infection, n(%) | ||||
| Abdominal | 88 (38.8%) | 56 (38.6%) | 0.99 (0.65~1.53) | 0.440 |
| Respiratory tract | 59 (26.0%) | 43 (29.7%) | 1.20 (0.76~1.91) | 0.978 |
| Urinary tract | 35 (23.1%) | 19 (14.3%) | 0.83 (0.45~1.51) | 0.536 |
| Skin and soft tissue | 28 (12.3%) | 24 (16.8%) | 1.41 (0.78~2.54) | 0.253 |
| Positive blood culture, n(%) | 81 (35.8%) | 51 (35.2%) | 0.97 (0.63~1.52) | 0.896 |
| SAPS II score at onset of shock | ||||
| Median(25th, 75th) | 46.0 (39.0, 55.0) | 53.00 (45.0, 61.0) | <0.001 | |
| SOFA score at onset of shock | ||||
| Median (25th, 75th) | 9.0 (6.0, 11.0) | 10.00 (8.00 14.0) | <0.001 | |
| Duration of shock, Days | ||||
| Median (25th, 75th) | 4.0 (3.0, 6.0) | (3.0, 10.0) | <0.001 | |
| Interventions | ||||
| Steroid treatment | 88 (38.8%) | 85 (58.6%) | 2.24 (1.46~3.42) | <0.001 |
| blood transfusion | 156 (68.7%) | 120 (82.8%) | 2.19 (1.31~3.83) | 0.003 |
| Total parenteral nutrition | 73 (32.2%) | 60 (41.2%) | 1.49 (0.97~2.30) | 0.070 |
| Renal replacement therapy | 27 (11.9%) | 36 (24.8%) | 2.45 (1.41~4.24) | 0.001 |
| Intubation | 70 (30.8%) | 98 (67.6%) | 4.68 (2.99~7.32) | <0.001 |
| Deep vein catheterization | 182 (80.2%) | 126 (86.9%) | 1.64 (0.92~2.94) | 0.094 |
| Length of ICU stay | ||||
| Median (25th, 75th) | 6 (4, 10) | 11 (6, 19) | <0.001 | |
| ICU mortality, n(%) | 58 (25.6%) | 62 (42.8%) | 0.001 | |
| Length of hospital stay | ||||
| Median (25th, 75th) | 13 (8, 20) | 19 (11, 33) | <0.001 | |
| In-hospital mortality, n(%) | 59 (26.0%) | 69 (47.6%) | <0.001 | |
| Death due to withdrawal of care, n(%) | 12 (20.7%) | 15 (24.1%) | 0.067 | |
SAPS II: Simplified Acute Physiology Socre II; SOFA: Sequential Organ Failure Assessment; CI95: 95% confidence intervals; OR: odds ratio.