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. 2016 Dec 7;6:38733. doi: 10.1038/srep38733

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Copyright © 2016, The Author(s)

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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TEM (A,B) and FIB-SEM (C,D) images of SH-SY5Y cells incubated with PEI-MNPs and PAA-MNPs for 24 hours. The TEM images of (A) PEI-MNPs and (B) PAA-MNPs show that the internalized particles formed clusters. The FIB-SEM images of the same cells show the presence of dense agglomerates of (C) PEI-MNPs and (D) PAA-MNPs attached to and crossing the cell membrane.