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. 2016 Dec 7;6:37927. doi: 10.1038/srep37927

Figure 2. Cardiac dysfunction in transgenic mice with cardiac-specific overexpression of Omi/HtrA2.

Figure 2

(a) Echocardiography of WT and transgenic mice overexpressing cardiac-specific Omi/HtrA2 (TG-Omi). (b) EF (ejection fraction), %. (c) FS (fractional shortening), %. (d) Doppler imaging of the mitral annulus. (e) E/A ratio, the ratio of the early (E) to late (A) ventricular filling velocities. (f) IVRT (isovolumetric relaxation time). All indices were recorded at 9 months age. n = 3–5 /genotype. **p < 0.01 versus WT.