Table 1.
Expression of microRNA-124 and clinicopathological factors in 80 breast cancer patients*
| Variable | No. of cases | Mean expression | P |
|---|---|---|---|
| Samples | |||
| tumor |
80 |
1.00 ±0.67 |
0.0016† |
| normal |
80 |
2.65±0.91 |
|
| Age (years) | |||
| <50 |
16 |
1.12±0.56 |
0.36 |
| >50 |
64 |
0.95±0.51 |
|
| Tumor size (cm) | |||
| <5 |
33 |
0.81±0.59 |
0.033† |
| >5 |
47 |
1.15±0.52 |
|
| Stage | |||
| I |
11 |
0.87±0.66 |
0.061 |
| II-IV |
69 |
1.02±0.59 |
|
| Histology | |||
| infiltrating duct |
51 |
0.98±0.65 |
0.58 |
| infiltrating lobular |
29 |
1.06±0.61 |
|
| Lymph node metastasis | |||
| absent |
25 |
1.09±0.71 |
0.45 |
| present |
55 |
0.95±0.57 |
|
| Estrogen-receptor status | |||
| positive |
52 |
0.95±0.55 |
0.67 |
| negative |
28 |
1.11±0.63 |
|
| Progesterone receptor status | |||
| positive |
39 |
1.03±0.55 |
0.58 |
| negative |
41 |
0.97±0.59 |
|
| Human epidermal growth factor receptor 2 status | |||
| positive |
32 |
0.81±0.51 |
0.024† |
| negative | 48 | 1.13±0.68 | |
*Data are presented as means ± standard deviation. Mean expression of all tumor samples was normalized to 1.00.
†P < 0.05, t-test.