Table 1. Relationships between miR-96-5p expression level and other SLE parameters and between miR-182-5p expression level and other SLE parameters.
Parameter | miR96-5p | miR182-5p | ||
---|---|---|---|---|
Pearson’s correlation coefficient | P value (two-tailed) | Pearson’s correlation coefficient | P value (two-tailed) | |
miR96-5p | 1 | — | 0.960 | <0.001 |
miR182-5p | 0.960 | <0.001 | 1 | — |
Spleen weight | 0.766 | 0.001 | 0.753 | 0.001 |
Lymph node weight | 0.732 | 0.001 | 0.708 | 0.002 |
Spleen weight/body weight | 0.772 | <0.001 | 0.750 | 0.001 |
Lymph node weight/body weight | 0.718 | 0.002 | 0.693 | 0.003 |
BUN | 0.135 | 0.619 | 0.051 | 0.850 |
Glomerular IgG deposition | 0.606 | 0.013 | 0.621 | 0.010 |
Glomerular C3 deposition | 0.915 | <0.001 | 0.904 | <0.001 |
Urine protein, 40 weeks of age | 0.319 | 0.229 | 0.273 | 0.306 |
Urine creatinine, 40 weeks of age | 0.224 | 0.403 | 0.393 | 0.132 |
Urine protein/creatinine, 40 weeks of age | 0.260 | 0.332 | 0.164 | 0.544 |
Anti-dsDNA antibody, 40 weeks of age | 0.734 | 0.001 | 0.631 | 0.009 |
CD138 | 0.930 | <0.001 | 0.918 | <0.001 |
ROR-γt+ | −0.151 | 0.699 | −0.182 | 0.638 |
T-bet+ | 0.659 | 0.054 | 0.699 | 0.036 |
GATA3+ | −0.062 | 0.874 | −0.052 | 0.894 |
CD4+CD25+ | −0.651 | 0.057 | −0.642 | 0.062 |
ROR-γt+ of CD4+ CD25+ | 0.143 | 0.713 | 0.008 | 0.984 |
Tbet+ of CD4+ CD25+ | 0.844 | 0.004 | 0.815 | 0.007 |
GATA+ of CD4+ CD25+ | −0.114 | 0.770 | −0.127 | 0.745 |
CD4+ CD25+ Foxp3+ | −0.829 | 0.006 | −0.804 | 0.009 |
CD4+ CD25+ ROR-γt+ | −0.284 | 0.458 | −0.396 | 0.291 |
CD4+ CD25+T-bet+ | 0.056 | 0.887 | 0.038 | 0.923 |
CD4+CD25+GATA3+ | −0.210 | 0.588 | −0.219 | 0.571 |
Treg/Th17 | −0.392 | 0.297 | −0.249 | 0.518 |
Th1/Th2 | 0.829 | 0.006 | 0.841 | 0.004 |
Pearson’s correlations were used to evaluate the relationships miRNA expression levels and other SLE parameters. Correlations were defined as weak (<0.3), moderate (0.3–0.7), or strong (>0.7). SLE: systemic lupus erythematosus, BUN: blood urea nitrogen.