Table 3.

Ratios of mRNA levels to that of Nrf2 by percentage in colorectal cancer.

%		Keap1/Nrf2	Bach1/Nrf2	Hmox1/Nrf2
Normal tissue		107.1 (88.8–198.9)∗	100.0 (76.5–107.2)∗	105.1 (92.7–137.0)∗
Tumor		109.6 (102.3–146.0)	102.2 (95.2–116.0)	100.0 (84.4–136.5)
	Distant metastasis
Normal tissue	With	108.6 (101.0–140.2)	100.0 (90.0–106.7)	106.3 (96.7–137.0)
	Without	106.9 (88.8–198.9)	100.0 (76.5–107.3)	104.3 (92.7–135.8)
Tumor	With	109.1 (105.0–116.0)	102.2 (98.0–106.0)	97.4 (84.4–111.1)∗∗
	Without	109.6 (102.0–146.0)	102.2 (95.0–116.0)	101.0 (92.7–136.5)

^∗Significantly different between the tumor and normal tissues by Wilcoxon signed ranks test.

^∗∗Significantly different between tissues of subjects with or without distant metastasis by Mann–Whitney test.