Table 3.

Risk factors for hospitalisation for anxiety and mood disorders in HIV-infected and –uninfected gay and bisexual men

Variable	Level	Multivariate
		Events	PYs	Rate p. 100 Pys (95%CI)	IRR	95% CI	P-value
HIV status‡	HIV-uninfected	181	13025	1.39 (1.20–1.61)	1
	HIV-infected	300	5580	5.38 (4.80–6.02)	2.49	1.47–4.21	0.001
Age, years§‡	18–35	54	4128	1.31 (1.00–1.71)	1
	36–45	153	6949	2.20 (1.88–2.58)	1.45	0.99–2.11
	46–55	202	5177	3.90 (3.40–4.48)	2.36	1.50–3.72
	55+	72	2349	3.06(2.43–3.86)	1.99	1.15–3.46	0.0015
Employment	Employed	218	14308	1.52 (1.33–1.74)	1
	Unemployed	252	3906	6.45 (5.70–7)	2.41	1.41–4.12	0.005
Sexual identity	Gay, queer or homosexual	414	17519	2.36 (2.15–2.60)	1
	Bisexual /Other	67	1085	6.17 (4.86–7.84)	5.24	2.34–11.74	<0.001
Religious belief	No	194	10100	1.92 (1.67–2.21)	1
	Yes	280	8248	3.39 (3.02–3.82)	2.21	1.40–3.49	0.003
Reported as having sought counselling for mental health in previous 12 months	No	154	13437	1.15 (1.00–1.34)	1
	Yes	326	5150	6.33 (5.68–7.06)	4.25	2.96–8.27	<0.001
Daily Smoker	No	163	11158	1.46 (1.25–1.70)	1
	Yes	297	7063	4.21 (3.75–4.71)	1.94	1.22–3.08	0.006
Number of Alcoholic drinks consumed in one sitting (on average)	Non-drinker	65	1210	5.37 (4.21–6.84)	1
	1 or 2	139	5915	2.35 (1.99–2.77)	0.36	0.15–0.87
	3 or 4	158	7324	2.16 (1.85–2.52)	0.69	0.28–1.68
	5 to 8	62	3052	2.03 (1.58–2.61)	0.63	0.23–1.72
	>9	52	909	5.72 (4.36–7.50)	1.66	0.50–5.50	0.021
Only tested in the HIV-infected cohort
Previously hospitalised for HIV-related dementia§†	No	224	5439	1.42 (3.61–4.69)	1
	Yes	76	140	54.18 (43.27–67.84)	3.08	1.78–5.30	<0.001
Year diagnosed HIV positive†	1980–1985	59	1570	3.57(2.91–4.85)	1
	1986–1991	115	1602	7.18 (5.98–8.62)	1.92	0.98–7.22
	1992–1996	37	1292	2.86 (2.07–3.95)	1.93	0.98–8.56
	1996–2006	82	1012	8.10 (6.52–10.06)	2.40	1.29–12.15	0.025s
Self-reported CD4 T-cell count†	<350	160	1404	11.40 (9.76–13.31)	1
	351–500	30	1043	2.88 (2.01–4.11)	0.20	0.07–0.56
	501–750	61	1360	4.48 (3.49–5.76)	0.33	0.13–0.85
	over 750	33	1183	2.79 (1.98–3.92)	0.23	0.08–0.63	0.004

^§Time-updated

^‡Significant age and HIV status interaction, p-value<0.0001

^†Only tested in HIV-infected cohort, adjusted for age, employment, sexual identity, religious belief, prior counselling for mental health, smoking, alcohol consumption and other significant HIV-related risk factors

^ssignificant linear trend

Abbreviations: p. 100Pys= per 100 person-years, 95%CI=95% Confidence Intervals, IRR=Incidence Rate Ratio