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. 2016 Dec 7;16:938. doi: 10.1186/s12885-016-2980-z

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© The Author(s). 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Short circuit current in biopsies from a control patient (a) and a CRN patient (b). The rolipram-induced increase in SCC observed in CTRLs (a) is not observed in CRN-patients (b). Biopsies mounted in the MUAS chambers were exposed to: amiloride (20 μM), indomethacin (13 μM), theophylline (100 μM), bumetanide (25 μM) and ouabain (200 μM)