Fig. 3.

a The concentration of HGF, KGF, VEGF and EGF in rat lung homogenate at different days post injury using enzyme linked immunosorbent assay (ELISA). *P = 0.028, **P = 0.013. b HGF accelerates AEC2 cell cycle in vitro. *P = 0.042, **P = 0.011. c The effect of ALI on the expression of key protein of the HGF/c-Met signaling. Image-J was used in the comparing of the intensity of bands of Western Blot. The 3rd day after ALI’s LTH can promote the significant higher expression of p-c-Met, *p = 0.018. d The effect of the 3rd day after ALI’s LTH on the proliferation of AEC2’s in vitro. AEC2’s had an increased proliferation rate when co-cultured with the 3rd day after ALI’s LTH (100ug/ml, 48 h). When co-cultured with SU11274, the proliferation rate of AEC2s co-cultured with the 3rd day after ALI’s LTH was inhibited (left). The quantitative analysis of AEC2 proliferation with or without SU11274 (right), *P = 0.004