Fig. 2.

nipi-3(0) lethality is suppressed by loss of cebp-1 or components of a PMK-1/p38 MAPK cascade. a Schematic overview of the forward genetic screen designed to identify the suppressors of nipi-3(0) larval arrest and lethality. b–g The mutations isolated from the nipi-3(0) suppressor screen and the deletion null mutations tested for nipi-3(0) suppression assay are shown in the left column and bright-field images of worms at 3 days post-hatching are shown in the right column. h Body length (μm) of worms at 3 days post-hatching. Each dot represents a single animal measured as shown; each red line represents the mean value; some data are replicated from Fig. 1 as shown with darker grey dots. ***P < 0.001; ns, not significant (one-way ANOVA with Tukey’s post hoc tests)