Table 2. Percentage of mothers with detectable maternal HIV RNA by study arm, week postpartum, and infant's 28 week HIV-infection status.*.
| Maternal ARV arm | Infant NVP arm | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Total mothers tested | Detectable plasma HIV RNA | Total mothers tested | Detectable breastmilk HIV RNA | Total mothers tested | Detectable plasma HIV RNA | Total mothers tested | Detectable breastmilk HIV RNA | |||||
| N | n | (%) | N | n | (%) | N | n | (%) | N | n | (%) | |
| HIV-transmitting mothers | ||||||||||||
| 2 weeks | 8 | 7 | (88) | 13 | 2 | (15) | 6 | 6 | (100) | 6 | 1 | (17) |
| 4 weeks | -- | -- | -- | 11 | 3 | (27) | -- | -- | -- | 6 | 3 | (50) |
| 6 weeks | 15 | 15 | (100) | 9 | 3 | (33) | 8 | 8 | (100) | 5 | 3 | (60) |
| 8 weeks | -- | -- | -- | 8 | 2 | (25) | -- | -- | -- | 6 | 4 | (67) |
| 12 weeks | 12 | 11 | (92) | 7 | 3 | (43) | 8 | 8 | (100) | 6 | 5 | (83) |
| 18 weeks | 4 | 4 | (100) | 5 | 3 | (60) | 1 | 1 | (100) | 4 | 2 | (50) |
| 24 weeks | 9 | 8 | (89) | 3 | 1 | (33) | 8 | 8 | (100) | 3 | 2 | (67) |
| Overall median log10 copies/ml (IQR) | 3.9 (2.3-4.7) | 1.7 (1.7-2.1) | 4.1 (3.4-4.8) | 1.9 (1.7-2.7) | ||||||||
| Non-transmitting mothers | ||||||||||||
| 2 weeks | 74 | 63 | (85) | 90 | 14 | (16) | 82 | 78 | (95) | 101 | 15 | (15) |
| 4 weeks | -- | -- | -- | 87 | 15 | (17) | -- | -- | -- | 106 | 38 | (36) |
| 6 weeks | 97 | 71 | (73) | 89 | 9 | (10) | 111 | 108 | (97) | 96 | 50 | (52) |
| 8 weeks | -- | -- | -- | 91 | 7 | (8) | -- | -- | -- | 93 | 53 | (57) |
| 12 weeks | 93 | 51 | (55) | 85 | 12 | (14) | 105 | 105 | (100) | 92 | 45 | (49) |
| 18 weeks | 55 | 32 | (58) | 72 | 9 | (13) | 70 | 70 | (100) | 89 | 45 | (51) |
| 24 weeks | 71 | 39 | (55) | 62 | 9 | (15) | 92 | 92 | (100) | 78 | 40 | (51) |
| Overall median log10 copies/ml (IQR) | 2.2 (1.6-3.2) | 1.7 (1.7-1.7) | 4.2 (3.2-4.9) | 1.7 (1.7-2.4) | ||||||||
*
Plasma specimens were not collected at week 4 or week 8. Plasma HIV RNA concentrations ≥40 copies/ml and breastmilk HIV RNA concentrations ≥56 copies/ml were considered detectable