Table 3. Mean difference in log10 maternal plasma HIV RNA by adherence category.
| Complete case | Imputed Unadjusted | |||||||
|---|---|---|---|---|---|---|---|---|
| Unadjusted | Adjusted* | Unadjusted | Adjusted* | |||||
| Mean diff** | (95% CI) | Mean diff** | (95% CI) | Mean diff** | (95% CI) | Mean diff** | (95% CI) | |
| Maternal and Infant Arm | ||||||||
| 81-98% adherent vs 0-80% | -0.82 | (-1.09, -0.55) | -0.93 | (-1.19, -0.68) | -0.45 | (-0.76, -0.15) | -0.52 | (-0.82, -0.22) |
| >98% adherent vs 0-80% | -0.69 | (-0.93, -0.45) | -0.75 | (-0.98, -0.52) | -0.37 | (-0.65, -0.08) | -0.42 | (-0.70, -0.15) |
| Maternal arm only† | ||||||||
| 81-98% adherent vs 0-80% | -0.07 | (-0.45, 0.30) | -0.08 | (-0.45, 0.29) | 0.01 | (-0.31, 0.33) | 0.01 | (-0.31, 0.33) |
| >98% adherent vs 0-80% | 0.09 | (-0.25, 0.44) | 0.10 | (-0.24, 0.44) | 0.11 | (-0.19, 0.41) | 0.12 | (-0.18, 0.41) |
*
Adjusted for: baseline maternal age, baseline maternal CD4+ count, baseline log10 plasma viral load, and nutrition randomization
**
Mean difference in log10 maternal plasma viral load by adherence category (referent: 0-80% adherence), based on mixed linear regression with log10 plasma viral load as outcome
†
In complete case analyses, a total of 47, 89, and 117 pill count adherence measures were in the 0-80%, 81-98%, and >98% adherence categories, respectively