Figure 2.

Older age at biopsy was associated with higher percentage of globally sclerotic glomeruli and lower kidney function. (A) Association of age at biopsy with percentage of globally sclerotic glomeruli (solid line; P<0.001). Age–matched estimated percentage of globally sclerotic glomeruli (line with stars) was generated using the 95% upper limit of globally sclerotic glomeruli present in a large cohort of healthy living kidney donors (on the basis of an average of 16 glomeruli per biopsy) (16). (B) Association of age at biopsy with eGFR (P<0.01).