Synteny of Gene Clusters for CPAMD8, A2M, PZP, Mug1, and Mug2 in Different Species
(A) Schematic depicting CPAMD8 flanked by HAUS8 and SIN3B in different species. X indicates deletion of CPAMD8 from the syntenic region in rat and mouse genomes. Flanking genes are shown as arrows.
(B) Schematic showing the clustered location of A2M and PZP in different species and Mug1 and Mug2 on the same chromosome in rodents. The chromosomal position of Mug1 and Mug2 adjacent to A2m and Pzp suggests that they are a result of tandem duplication. The distance of the genes depicted is not to scale.
Gene orientation is indicated by the arrowhead.