Fig. 6.

Effect of acetylcholine on mucociliary transport by gut-corrected CF and non-CF pig tracheas. Basal rates of mucociliary transport in non-CF tracheas were measured in individual tissues over three consecutive 20-min periods. Acetylcholine (ACh, 100 μM) was then added to the bath and the mucociliary transport was again measured over three consecutive 20-min periods. Dotted lines show the 95% confidence intervals for non-CF percent solids in each group. The mucociliary transport responses to ACh for both CF tracheas in the bottom graph were outside of the 95% confidence intervals of the responses of non-CF tracheas (‡) for all three ACh exposure periods. Each line represents responses of a different trachea.