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Severe hepatomegaly in Atg7F/FAlb-Cre+ mice but not in Atg7+/+Alb-Cre+ mice. A: body weight of Atg7+/+Alb-Cre+ and Atg7F/FAlb-Cre+ mice was not significantly different (P = 0.098). B: macroscopic view of an Atg7+/+Alb-Cre+ (left) and Atg7F/FAlb-Cre+ (right) mouse illustrating the prominent hepatomegaly in Atg7F/FAlb-Cre+ mice. C: hepatomegaly is also reflected by a significantly higher liver weight-to-body weight ratio in Atg7F/FAlb-Cre+ mice (***P < 0.001).
