Fig. 6.

Fibrotic pathology is preserved in the absence of CCR2 signaling. A and B: H&E staining of FFPE lung sections showing either B6-to-B6 syngeneic transplant (WT BMT) or CCR2^−/−-to-B6 transplant at 21 dpi. C and D: Masson's trichrome staining of FFPE lung sections showing either B6-to-B6 syngeneic transplant or CCR2^−/−-to-B6 transplant at 21 dpi. E and F: high-power (×600 magnification) fields of fibrotic areas from either WT or CCR2^−/− BMT (respectively) lung sections harvested 21 dpi and stained with H&E. Yellow arrowheads show the location of infiltrating segmented/banded granulocytes. Images are representative of 3 separate experiments n = 3–4 mice per group per experiment.