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. 2016 Jul 27;311(4):F822–F829. doi: 10.1152/ajprenal.00589.2015

Fig. 9.

Fig. 9.

Sulprostone increases AQP2 mRNA accumulation and trafficking to the plasma membrane in response to hypertonic saline. Rats were pretreated with vehicle or sulprostone for 3 days while ingesting a normal diet and tap water. AQP2 mRNA assessed by qRT-PCR (A) and AQP2 expression determined by immunohistochemical analysis (B) were increased in sulprostone-treated rats that were then given 1% NaCl in the drinking water for 3 days. The data in A are presented as means ± SE; n = 4; representative figures are shown in B.