Fig. 1.

The workflow and logic architecture of Biological Information Gatherer (BIG). The BIG is accessible through a web browser. Users submit the queries from the web browsers, and the embedded PHP codes (a scripting programing language for web site development) are executed to retrieve queried information from the MySQL database. The database was constructed based on a large dataset integrated from multiple individual experimental datasets. These databases are listed at https://hpcwebapps.cit.nih.gov/ESBL/Database/.