Assessment of tendon structure. Tendon disorganization (A) was higher (P < 0.001) and tendon echogenicity (B) lower (P < 0.001) in all groups after injury. Males were relatively more disorganized than females at 3 wk (+38.1% in male vs. female, P = 0.025). By 6 wk, normalized echogenicity was greater in male tendons (+23.6% in male vs. female, P = 0.004). In contrast to the effect of sex, ovariectomy had no effect on HFUS measures. CSA (C) was greater after injury (P < 0.001) for all groups. Normalized CSA grew significantly in OVX between 3 and 6 wk (+130.1% at 6 vs. 3 wk, P = 0.008) and by 6 wk was greater than females (+216.5% vs. female, P < 0.001). “Pre” indicates preinjury values. Solid lines indicate significant differences (P < 0.05); dashed lines indicate trends (P < 0.10). #Significant differences from preinjury (P < 0.05); ###all values differ from preinjury (P < 0.05); *P < 0.05; **P < 0.01; ***P < 0.001. All P values have been corrected for multiple comparisons. Error bars indicate standard deviation.