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Exercise regulation of energy balance in Wt and Fgf21−/− mice. Weekly average body weight measurements of Wt (exercised, EX, ■, n = 5; sedentary, SED, ●, n = 4) (A) and Fgf21−/− (EX, □, n = 8; SED, ○, n = 10) (C) are shown. Percent body weight gain from initial in Wt (B) and Fgf21−/− (D) mice is shown. E: change in body weight (final-initial). All data are represented as means ± SE. *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001 compared with sedentary control.
