Table 3.
Renal function during the follow-up period
| Variables | Pulmonary vein isolation |
Pulmonary vein isolation + renal sympathetic denervation |
||||||
|---|---|---|---|---|---|---|---|---|
| Baseline | 3rd mo | 6th mo | 12th mo | Baseline | 3rd mo | 6th mo | 12th mo | |
| Cr (mg/dL) | 1.2 ± 0.2 | 1.2 ± 0.2 | 1.2 ± 0.2 | 1.3 ± 0.2∗† | 1.3 ± 0.2 | 1.1 ± 0.2∗ | 1.1 ± 0.2∗∗ | 1.1 ± 0.2∗∗ |
| eGFR (mL/min/1.73 m2) | 60.5 ± 15.9 | 59.1 ± 15.4 | 58.3 ± 14.0 | 56.6 ± 14.7∗† | 59.3 ± 13.3 | 62.5 ± 12.2∗ | 64.9 ± 13.4∗∗ | 65.7 ± 14.0∗∗ |
| ACR (mg/g) | 77.5 (62.3–82.8) | 82.5† (66.3–87.8) | 84.5†† (68.3–89.8) | 86.5†† (69.3–91.8) | 85.0 (66.0–116.0) | 44.0∗ (31.0–74.0) | 31.0∗∗ (21.0–53.0) | 19.0∗∗ (11.5–32.5) |
Data are presented as mean ± SD or median (interquartile range).
∗P < 0.05 and ∗∗P < 0.001 for values at 3rd, 6th, and 12th months versus baseline. †P < 0.05 and ††P < 0.0001 for comparisons between pulmonary vein isolation and pulmonary vein isolation + renal sympathetic denervation at the same time point.
ACR, albumin:creatinine ratio; Cr, creatinine; eGFR, estimated glomerular filtration rate.