Table 5.
Parameters | Control | PCOS | Metformin | Rutin-I | Rutin-II |
---|---|---|---|---|---|
ROS (U/min) | 0.20 ± 0.04 | 0.39 ± 0.09a* | 0.17 ± 0.02b* | 0.19 ± 0.02b* | 0.16 ± 0.01b* |
TBARS (nmol/min/mg) | 5.69 ± 1.07 | 16.06 ± 1.25a** | 10.78 ± 1.07 | 8.93 ± 2.45b* | 8.15 ± 0.82b* |
LOOH (nmol/min/mg) | 3.29 ± 0.48 | 5.39 ± 0.29a* | 3.44 ± 0.47 | 3.59 ± 0.63 | 3.23 ± 0.42b* |
CAT(U/min) | 4.93 ± 0.08 | 3.49 ± 0.33a* | 4.15 ± 0.47 | 4.22 ± 0.28 | 4.49 ± 0.38 |
POD(nmole) | 12.09 ± 0.72 | 9.29 ± 0.01a* | 10.44 ± 0.62 | 10.11 ± 0.58 | 11.87 ± 0.59b* |
SOD (U/min) | 5.81 ± 0.24 | 2.74 ± 0.29a* | 5.51 ± 0.51b* | 5.41 ± 1.08b* | 5.72 ± 0.51b* |
GSR (U/mol/mg) | 3.96 ± 0.38 | 1.79 ± 0.09a* | 3.89 ± 0.29b* | 3.46 ± 0.71 | 4.67 ± 0.52b* |
GST (U/mol/mg) | 10.85 ± 0.21 | 8.02 ± 0.83a** | 9.47 ± 0.28 | 9.37 ± 0.48 | 10.91 ± 0.22b* |
GSH (U/mol/mg) | 6.91 ± 0.50 | 4.97 ± 0.14a** | 6.55 ± 0.48b* | 6.39 ± 0.02b* | 6.77 ± 0.88b** |
GSH-px (U/mol/mg) | 29.87 ± 2.14 | 20.35 ± 0.64a** | 25.34 ± 2.11 | 24.24 ± 1.76 | 30.10 ± 1.29b** |
Values are expressed as Mean ± SEM
*=p< 0.05, **=p< 0.01
aValue vs control, bValue vs PCOS