Table 6.
Effect of Rutin-I (100 mg/kg) and Rutin-II (150 mg/kg) on serum testosterone, estradioland progesterone concentrations in Letrozole induced PCOS rats after 36 days of experiment
| Hormonal concentrations | Control | PCOS | Metformin | Rutin-I | Rutin-II |
|---|---|---|---|---|---|
| Testosterone (ng/ml) | 1.88 ± 0.71 | 10.19 ± 0.76a*** | 4.51 ± 0.30 b** | 5.77 ± 0.68b* | 8.21 ± 1.85a** |
| Estradiol (ng/ml) | 19.41 ± 2.21 | 14.26 ± 2.70 | 28.57 ± 4.32 | 34.83 ± 8.26 | 27.25 ± 0.48 |
| Progesterone (pg/ml) | 43.43 ± 8.81 | 12.76 ± 3.75a** | 22.98 ± 4.85 | 19.66 ± 5.34a* | 24.63 ± 3.46 |
Values are expressed as Mean ± SEM
*=p< 0.05, **=p< 0.01, ***=p< 0.001
aValue vs control, bValue vs PCOS