Table 7.

Effect of Rutin-I (100 mg/kg) and Rutin-II (150 mg/kg) on total cholesterol, triglycerides, HDL- C, LDL-C, VLDL-C, Non-HDL-C, TC/HDL, TG/HDL and LDL/HDL concentrations in Letrozole induced PCOS rats after 36 days of experiment

Parameters	Control	PCOS	Metformin	Rutin-I	Rutin-II
Total Cholesterol(mg/dL)	215.60 ± 3.43	231.10 ± 4.27	211.30 ± 6.81b*	212.21 ± 1.53b*	207.10 ± 2.24b**
Triglycerides (mg/dL)	185.11 ± 4.23	213.10 ± 5.16a*	197.40 ± 5.82	199.20 ± 6.93	186.12 ± 4.62b*
HDL-C (mg/dL)	160.70 ± 4.17	144.41 ± 3.63a*	153.21 ± 1.80	146.43 ± 4.52	159.80 ± 3.14b*
LDL-C (mg/dL)	17.83 ± 3.98	42.99 ± 1.99a**	18.58 ± 7.22b**	25.81 ± 5.11	10.05 ± 2.29b***
VLDL-C (mg/dL)	37.03 ± 0.85	42.61 ± 1.03a*	39.49 ± 1.16	39.83 ± 1.39	37.20 ± 0.92b*
Non-HDL-C(mg/dL)	54.86 ± 4.48	85.61 ± 1.50a**	58.07 ± 7.32b**	65.65 ± 4.75b*	47.24 ± 2.64b***
TC/HDL	1.34 ± 0.03	1.59 ± 0.02a***	1.38 ± 0.05b**	1.45 ± 0.04	1.29 ± 0.02b***c*
TG/HDL	1.16 ± 0.04	1.48 ± 0.06a**	1.29 ± 0.03	1.37 ± 0.06	1.17 ± 0.04b**
LDL/HDL	0.11 ± 0.03	0.29 ± 0.01a**	0.12 ± 0.05b**	0.18 ± 0.04	0.06 ± 0.02b***

Values are expressed as Mean ± SEM

* = p < 0.05, ** = p < 0.01, *** = p < 0.001

^a Value vs control, ^b Value vs PCOS, ^c Value vs Metformin