Table 2.
Minimum inhibitory concentration (MIC) and Minimum bactericidal and fungicidal concentrations (MBC, MFC) of acthaside (μg/ml) from A. ataxacantha against microorganisms
| Minimum inhibitory concentrations (μg/ml) | ||||||
|---|---|---|---|---|---|---|
| Microorganismsa | Gram (+) bacteria | Gram (-) bacteria | Yeast | |||
| S.a | S.a.m.r | S. ep | E.f | P.a | C. a | |
| Isolated compoundb | 50 | 50 | 25 | 50 | 50 | 25 |
| Gentamicin | 0.39 | 0.39 | 0.78 | 0.39 | 0.78 | Nt |
| Fluconazole | Nt | Nt | Nt | Nt | Nt | 0.78 |
| Minimum bactericidal and fungicidal (μg/ml) | ||||||
| Isolated compoundb | 50 | 50 | 25 | 50 | 50 | 25 |
| Gentamicin | 0.78 | 1.56 | 1.56 | 0.78 | 1.56 | Nt |
| Fluconazole | Nt | Nt | Nt | Nt | Nt | 1.56 |
| MIC index | ||||||
| Isolated compound | 1 | 1 | 1 | 1 | 1 | 1 |
| Gentamicin | 2 | 4 | 2 | 2 | 2 | Nt |
| Fluconazole | Nt | Nt | Nt | Nt | Nt | 2 |
a S. a : Staphylococcus aureus; S.a.m.r : Staphylococcus aureus methicillin resitant; S.ep : Staphylococcus epidermidis; E. f: Enterococcus faecalis; P. a: Pseudomonas aeruginosa; C. a: Candida albicans. Nt not tested
bisolated compound: 7-hydroxy-2-methyl-6-[β-galactopyranosyl-propyl]-4H-Chromen-4-one (acthaside)