Table 1.
Summary of significantly enriched (P < 0.05) pathway terms associated with differentially expressed genes (DEGs)
| Classa | Pathway ID | Pathway term | Number of DEGs | P value* |
|---|---|---|---|---|
| I | PATH:01110 | Biosynthesis of secondary metabolites | 136 | 2.03E-05 |
| PATH:00940 | Phenylpropanoid biosynthesis | 37 | 4.43E-05 | |
| PATH:00910 | Nitrogen metabolism | 13 | 2.65E-04 | |
| PATH:00592 | alpha-linolenic acid metabolism | 13 | 3.56E-04 | |
| PATH:04075 | Plant hormone signal transduction | 33 | 3.64E-04 | |
| PATH:00062 | Fatty acid elongation | 11 | 1.09E-03 | |
| PATH:00945 | Stilbenoid, diarylheptanoid, and gingerol biosynthesis | 19 | 1.32E-03 | |
| PATH:00360 | Phenylalanine metabolism | 26 | 1.50E-03 | |
| PATH:01100 | Metabolic pathways | 180 | 1.98E-03 | |
| PATH:00941 | Flavonoid biosynthesis | 15 | 2.68E-03 | |
| PATH:04626 | Plant-pathogen interaction | 40 | 3.24E-03 | |
| PATH:00280 | Valine, leucine and isoleucine degradation | 10 | 3.70E-03 | |
| PATH:00052 | Galactose metabolism | 11 | 4.30E-03 | |
| PATH:00903 | Limonene and pinene degradation | 15 | 5.76E-03 | |
| PATH:00480 | Glutathione metabolism | 17 | 8.59E-03 | |
| PATH:00561 | Glycerolipid metabolism | 11 | 8.75E-03 | |
| PATH:00410 | beta-alanine metabolism | 7 | 2.00E-02 | |
| PATH:00900 | Terpenoid backbone biosynthesis | 9 | 2.43E-02 | |
| PATH:00760 | Nicotinate and nicotinamide metabolism | 4 | 4.37E-02 | |
| II | PATH:03008 | Ribosome biogenesis in eukaryotes | 31 | 2.77E-14 |
| PATH:03010 | Ribosome | 41 | 1.40E-08 | |
| PATH:00196 | Photosynthesis - antenna proteins | 10 | 1.20E-07 | |
| PATH:00230 | Purine metabolism | 19 | 1.24E-03 | |
| PATH:00240 | Pyrimidine metabolism | 16 | 2.67E-03 | |
| PATH:03013 | RNA transport | 19 | 3.63E-03 | |
| PATH:03018 | RNA degradation | 13 | 8.68E-03 | |
| PATH:03410 | Base excision repair | 7 | 1.31E-02 | |
| PATH:03450 | Non-homologous end-joining | 3 | 1.74E-02 | |
| PATH:03440 | Homologous recombination | 7 | 3.87E-02 | |
| PATH:03020 | RNA polymerase | 6 | 4.08E-02 | |
| III | PATH:01110 | Biosynthesis of secondary metabolites | 89 | 2.05E-13 |
| PATH:00940 | Phenylpropanoid biosynthesis | 26 | 2.69E-07 | |
| PATH:00010 | Glycolysis/Gluconeogenesis | 17 | 5.30E-06 | |
| PATH:00360 | Phenylalanine metabolism | 20 | 6.99E-06 | |
| PATH:00520 | Amino sugar and nucleotide sugar metabolism | 18 | 1.12E-05 | |
| PATH:00966 | Glucosinolate biosynthesis | 4 | 7.22E-04 | |
| PATH:00380 | Tryptophan metabolism | 7 | 1.19E-03 | |
| PATH:01100 | Metabolic pathways | 89 | 2.00E-03 | |
| PATH:00909 | Sesquiterpenoid and triterpenoid biosynthesis | 4 | 4.89E-03 | |
| PATH:00051 | Fructose and mannose metabolism | 7 | 8.44E-03 | |
| PATH:00904 | Diterpenoid biosynthesis | 5 | 8.62E-03 | |
| PATH:00052 | Galactose metabolism | 6 | 1.54E-02 | |
| PATH:00030 | Pentose phosphate pathway | 5 | 3.29E-02 | |
| PATH:00591 | Linoleic acid metabolism | 3 | 4.14E-02 | |
| PATH:00944 | Flavone and flavonol biosynthesis | 3 | 4.62E-02 | |
| IV | PATH:00500 | Starch and sucrose metabolism | 6 | 2.24E-03 |
| PATH:00196 | Photosynthesis - antenna proteins | 2 | 4.87E-03 | |
| PATH:00944 | Flavone and flavonol biosynthesis | 2 | 1.23E-02 | |
| V | PATH:01110 | Biosynthesis of secondary metabolites | 17 | 2.24E-03 |
| PATH:01100 | Metabolic pathways | 22 | 4.03E-03 | |
| PATH:00940 | Phenylpropanoid biosynthesis | 6 | 6.04E-03 | |
| PATH:00500 | Starch and sucrose metabolism | 5 | 9.00E-03 | |
| PATH:00944 | Flavone and flavonol biosynthesis | 2 | 1.10E-02 | |
| PATH:00902 | Monoterpenoid biosynthesis | 1 | 2.00E-02 | |
| PATH:00941 | Flavonoid biosynthesis | 3 | 2.31E-02 | |
| PATH:00460 | Cyanoamino acid metabolism | 2 | 3.62E-02 | |
| PATH:01110 | Biosynthesis of secondary metabolites | 17 | 2.24E-03 |
aClass numbers refer to Fig. 3
*P values for modified Fisher’s exact test