Skip to main content
. Author manuscript; available in PMC: 2017 Dec 1.
Published in final edited form as: Mol Carcinog. 2016 Jan 19;55(12):2168–2182. doi: 10.1002/mc.22459

Figure 4.

Figure 4

Gene expression alterations induced by (S)-NNN and (R)-NNN in OKF6 immortalized oral keratinocytes. Selected genes from those deregulated by (S)-NNN in esophageal and oral mucosa of rats were analyzed in RNA samples obtained from (S)-NNN-treated (unfilled bars) or (R)-NNN-treated (filled bars) OKF6 cells by qRT-PCR as described in Materials and Methods. Expression levels are shown in arbitrary units on the Y axis, whereas concentrations of the carcinogens are shown on the X axis. Statistical significance was assessed relative to the level of the genes in untreated OKF6 cells using one–way ANOVA and a post Tukey’s test; *P < 0.05