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. Author manuscript; available in PMC: 2016 Dec 7.
Published in final edited form as: JAMA. 2010 Oct 20;304(15):1684–1692. doi: 10.1001/jama.2010.1500

Figure 2.

Figure 2

Incidence of invasive breast cancer in the WHI clinical trial. Intent-to-treat Kaplan Meier cumulative hazard curves for incidence of invasive breast cancer by study group and time since randomization. Hazard ratios (HRs), 95% confidence intervals (CIs) and P values are from Cox regression models, stratified by age (5 year intervals) and randomization assignment in the WHI Dietary Modification trial. Quintiles of duration on study intervention (elapsed time from randomization until the intervention stopped on July 8, 2002) are indicated by the progressive shaded regions. For example, 80%, 60%, 40% and 20% of participants were in the intervention for at least 4.6 years, 5.2 years, 5.8 years and 6.7 years, respectively. All women stopped the intervention by 8.6 years (when shading ends).