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. 2016 Dec 7;15:209. doi: 10.1186/s12934-016-0601-9

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© The Author(s) 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 6 — Pharmacokinetics of IFN-α/Fc fusion proteins. SD rats (n = 3 per group) were intravenously administered a single dose of 30 µg/kg of the indicated samples via the vena caudalis. Blood samples were drawn prior to treatment and at 0.2, 8, 24, 48, 72, 96, 120 and 144 h after the treatment. The serum human IFN-α level was quantified using the CBA Human IFN-α Flex Set. All data are presented here as mean ± standard deviation of the concentrations