Table 1.

Induction of mRNA expression by IFN-α/Fc fusion proteins in PBMCs

Samples	OAS1	STAT1
IFN-α	19.59	1.67
IFN-α/Fc-WT	10.47	1.34
IFN-α/Fc-MD	10.60	1.41
IFN-α/Fc-SC	10.75	1.23
PEG-IFN-α	11.73	1.26
PBS	1.00	1.00

PBMCs were treated with 10 ng/mL of indicated samples. RNA was extracted and the level of induction was measured relative to untreated cells (PBS) by quantitative PCR

OAS1 2, 5-oligoadenylate synthetase 1, STAT1 signal transducer and activator of transcription 1