Table 1.
The changes of body weight, MWT and MWD of rats at different time points (n=10, χ̄± s).
| Time | Weight | MWT | MWD | ||||||
|---|---|---|---|---|---|---|---|---|---|
| C | S | CIBP | C | S | CIBP | C | S | CIBP | |
| T0 | 186.85±2.94 | 187.20±3.06 | 187.05±2.99 | 14.12±1.83 | 14.20±1.95 | 14.18±2.06 | 0.75±0.26 | 0.70±0.26 | 0.70±0.26 |
| T1 | 199.35±2.52 | 196.20±4.63 | 195.40±4.38 | 13.85±1.77 | 14.03±1.68 | 13.61±1.89 | 0.80±0.26 | 0.80±0.35 | 0.80±0.35 |
| T2 | 209.05±3.24 | 206.03±4.42 | 204.05±6.27 | 14.07±1.82 | 13.88±1.75 | 12.09±2.11 | 0.75±0.26 | 0.75±0.35 | 0.95±0.28 |
| T3 | 221.25±4.93 | 217.70±4.92 | 207.20±5.97*# | 14.16±1.78 | 13.91±1.80 | 9.54±1.56*# | 0.80±0.26 | 0.80±0.35 | 3.15±1.06*# |
| T4 | 231.50±4.22 | 231.95±4.13 | 212.80±5.62*# | 13.94±1.69 | 13.56±1.63 | 8.42±1.19*# | 0.80±0.26 | 0.80±0.34 | 5.15±1.20*# |
| T5 | 239.50±5.12 | 237.75±5.15 | 217.55±5.90*# | 14.08±1.84 | 13.81±1.79 | 7.87±0.98*# | 0.75±0.26 | 0.80±0.26 | 5.40±1.13*# |
| T6 | 245.40±5.57 | 243.10±6.10 | 215.65±6.25*# | 14.13±1.75 | 13.52±1.74 | 7.03±1.04*# | 0.80±0.26 | 0.80±0.35 | 5.60±1.02*# |
C group – healthy control group; S group – sham-operation group; CIBP group – cancer-induced bone pain group; MWT – mechanical withdrawal threshold; MWD – mechanical withdrawal duration; T0 – pre-operative Day 1; T1–6 – Day 3, 6, 9, 12 and 18 post CIBP modeling, respectively.
*
Compared with C group, P<0.05;
#
Compared with S group, P<0.05.