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. Author manuscript; available in PMC: 2017 Dec 1.
Published in final edited form as: Leuk Lymphoma. 2016 Apr 22;57(12):2804–2812. doi: 10.3109/10428194.2016.1170827

Table 2. Summary of immunophenotypic characterization of AITL by flow cytometry.

Antigen/pattern Bone marrow (%) Peripheral blood (%) Lymph node (%) Body fluid (%)
Surface CD3 (N = 97) N = 41 N = 16 N = 31 N = 9
Complete loss 26 (63.4) 13 (81.3) 12 (38.7) 2 (22.2)
Partial loss 1 (6.3) 4 (12.9)
↓intensity 12 (29.3) 2 (12.5) 15 (48.4) 4 (44.4)
↑Intensity 2 (4.9)
TCRαβ (N = 80) N = 39 N = 12 N = 22 N = 8
Complete loss 25 (64.1) 10 (83.3) 11 (50.0) 2 (25.0)
↓intensity 1 (2.6) 2 (16.7) 5 (22.7)
CD10 (N = 85) N = 36 N = 14 N = 27 N = 8
CD10+ 5 (13.9 %) 4 (28.6) 11 (40.7) 5 (62.5)
CD10+ (partial or subset) 13 (36.1 %) 5 (35.7) 13 (48.1) 2 (25)
CD7 (N = 86) N = 39 N = 14 N = 24 N = 9
Complete loss 16 (41.0) 4 (28.6) 9 (37.5) 8 (88.9)
Partial loss 9 (23.1) 1 (7.1) 1 (4.2) 1 (11.1)
↓intensity 2 (5.1) 1 (4.2)
↑Intensity 1
CD4 (N = 97) N = 41 N = 16 N = 31 N = 9
↓intensity 2 (4.9) 4 (12.9) 4 (44.4)
↑Intensity 1 (3.2)
CD52 (N = 81) N = 38 N = 13 N = 22 N = 8
Complete loss 5 (13.2)
↓intensity 2 (9.1)
CD5 (N = 89) N = 40 N = 15 N = 26 N = 8
Complete loss 1 (2.5) 1 (3.8)
CD2 (N = 85) N = 40 N = 14 N = 23 N = 8
Complete loss 1 (2.5)
CD8 (N = 97) N = 41 N = 16 N = 31 N = 9
Partial expression (CD4+/CD8+) 1 (2.4)

A subset of specimens showed more than one immunophenotypic aberrancy in one (e.g., partial loss and decreased intensity) or more antigens.