FIG 1 .
The roles of QS in resolving fermentative stress in V. cholerae. (A) Simplified view of the V. cholerae QS circuit. (B) Viability of luxOD61E ΔvpsL (red bars) and ΔluxO ΔvpsL (blue bars) mutant cells at 72 h of growth under fermentative and nonfermentative conditions. (C) Viability of luxOD61E (red bars) and ΔluxO (blue bars) mutants with additional QS mutations and the ΔluxO ΔaphA ΔhapR mutant strain carrying an empty plasmid or a plasmid overexpressing Qrr4 (black bar) at 72 h of growth under fermentative conditions. All strains are ΔvpsL mutants. The limit of detection at 72 h is 2 cells/ml of culture. The values shown are averages of at least three replicates. Error bars denote the SEM.