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. 2016 Dec 6;7(6):e01863-16. doi: 10.1128/mBio.01863-16

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Copyright © 2016 Hawver et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license.

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FIG 3 — Extracellular metabolite profiles of QS mutants grown under fermentative conditions. (A) Simplified view of glycolysis and pyruvate metabolism in V. cholerae. (B) Viability of LCD-locked (luxO^D61E ΔaphA ΔhapR ΔvpsL; red solid triangles) and HCD-locked (ΔluxO ΔaphA ΔhapR ΔvpsL; blue solid squares) cells. Concentrations (millimolar) of formate (C), acetate, (D), lactate (E), acetoin (F), and 2,3-BD (G) in LCD-locked (red solid triangles) and HCD-locked (blue solid squares) mutants. P values (Student’s t test): *, P < 0.05; **, P < 0.01; ***, P < 0.001; ****, P < 0.0001. The values shown are averages of at least three replicates. Error bars denote the SEM.