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Atomic force microscopy of pure and hybrid materials. Top left: Atomic force micrograph of pure polycaprolactone is mostly featureless, whereas surface features are rougher for 30% bone by mass (top right) and 70% bone by mass (bottom left). Quantification of root-mean-square roughness (bottom right) confirms these observations. *p < 0.05 by one-way ANOVA with posthoc Tukey test.
