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In vitro osteogenic gene expression. Gene expression of Runx2, osteocalcin, and osteonectin increased in cells cultured in hybrid scaffolds despite the absence of exogenous osteoinductive factors. Bottom right: With the addition of a phosphate source, calcium production per cell displayed the same trend. *p < 0.05 compared to cells cultured in pure polycaprolactone scaffolds by one-way ANOVA with posthoc Tukey test.
