Figure 2. Ethanol differentially impacts DC signaling depending on gender.

BM-DC generated from male and female mice were cultured for 9 days and treated with 50mM ethanol (EtOH) for 3hrs followed by LPS stimulation. DC were then lysed and assessed for accumulation of protein or phosphorylation of key signaling molecules involved in stimulating a pro-inflammatory, anti-tumor immune response. Data are representative of 3 separate experiments. *p>0.05