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. Author manuscript; available in PMC: 2017 Dec 6.
Published in final edited form as: Structure. 2016 Nov 3;24(12):2067–2079. doi: 10.1016/j.str.2016.09.012

Figure 8. A Communication Focal Point Involving the Cβ-clasp is Enhanced in AIF-CTC.

Figure 8

(A) Sequence plot of total mutual information values correlating active site dihedral conformations to the rest of AIF. No ligand (●), CTC (○).

(B) Scaled color maps of mutual information values for ligand-free (left) and CTC (right) trajectories highlighting increased active site correlation at the Cβ-clasp and central β-strand.

(C) Table of ranked total MI values for ligand-free and CTC trajectories. Residues associated with the central β-strand or the Cβ-clasp are indicated in bold.