Table 3.
Associations between kidney function and extent of coronary artery calcium by HIV infection status among those with coronary calcification. Shown are the results from the fully adjusted multiple linear regression model* (N=506).
| Exposure | HIV− (N=310) | HIV+ (N=196) | HIV− vs. HIV+ |
|---|---|---|---|
| Mean Differenceb (95% CI) | Mean Differenceb (95% CI) | P-valuea | |
| eGFR ≥ 90c (per 10-unit decrease) | 0.44 (0.02, 0.86) | −0.22 (−0.51, 0.07) | 0.01 |
| eGFR < 90c (per 10-unit decrease) | −0.08 (−0.32, 0.16) | −0.06 (−0.23, 0.10) | 0.92 |
| LN Uprcr (per 1-unit increase) | 0.75 (0.26, 1.25) | 0.22 (−0.03, 0.47) | 0.06 |
*
Adjusted for age, race and CAD risk factors (body mass index, systolic BP, use of hypertension medications, use of diabetes medications, fasting glucose, total and HDL cholesterol, use of lipid lowering medications and pack-years of tobacco smoking).
a
p-interaction
b
Mean difference in Log CAC score per change in exposure variable
c
ml/min/1.73m2
Bold indicates significant at 0.05 level