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. Author manuscript; available in PMC: 2017 Oct 1.
Published in final edited form as: Am J Transplant. 2016 Jul 14;16(10):3016–3023. doi: 10.1111/ajt.13907

Figure 3. CCR2 is detected by 64CuAuNCs-ECL1i with enhanced efficiency using PET.

Figure 3

(A) Representative 64CuAuNCs-ECL1i and 64CuAuNCs nanoclusters PET/CT images in B6 wildtype → B6 wildtype lung transplantation model at 24 hours following engraftment. The targeted nanocluster showed significant uptake in the donor lung while the non-targeted counterpart showed minimum non-specific retention. Quantitative uptake analysis of (B) 64CuAuNCs and (C) 64CuAuNCs-ECL1i in lung grafts and native lungs after B6 wildtype → B6 wildtype pulmonary transplantation and (D) Donor graft/native lung uptake ratios for 64CuAuNCs-ECL1i and 64CuAuNCs PET after B6 wildtype → B6 wildtype pulmonary transplantation. Circle: donor lung (n=4/group).