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. Author manuscript; available in PMC: 2017 Dec 15.
Published in final edited form as: Clin Cancer Res. 2016 Jun 7;22(24):6204–6216. doi: 10.1158/1078-0432.CCR-15-3059

Figure 1. H460-M clone exhibits resistance to cell death.

Figure 1

(A) Western blot analysis of indicated proteins expressed by the H460-E and H460-M clones. (B) Susceptibility of H460-E vs. -M clones to a range of indicated concentrations of cisplatin. (C) Percent of lysis mediated by brachyury-specific CD8+ T cells, (D) NK effector cells, and (E) recombinant TRAIL. (F) Expression of mRNA encoding for TRAIL, FAS, and decoy receptors (DcR1, DcR2, DcR3), relative to GAPDH. Error bars indicate the standard error of the mean (SEM) of triplicate measurements. [* p<0.05, ** p<0.01, *** p<0.001, **** p<0.0001].