Table 5. Allele and genotype frequencies of the KISS1R polymorphisms.

SNP	Group	Allele frequency				P value	Genotype frequency						P value
		1		2			11		12		22
c.-123C>T	CPP	363	0.936	25	0.064	0.672	170	0.876	23	0.119	1	0.005	0.753*
C=1, T=2	Control	187	0.944	11	0.056		88	0.889	11	0.111	0	0.000
c.24A>G	CPP	332	0.856	56	0.144	0.441	141	0.727	50	0.256	3	0.017	0.450*
A=1, G=2	Control	174	0.879	24	0.121		76	0.768	22	0.222	1	0.010
c.245-34G>A	CPP	322	0.83	66	0.170	0.513	132	0.680	58	0.299	4	0.021	0.559*
G=1, A=2	Control	160	0.808	38	0.192		64	0.647	32	0.323	3	0.030
c.505+42T>G	CPP	387	0.997	1	0.003	1.000	193	0.995	1	0.005	0	0.000	1.000*
T=1, G=2	Control	198	1.000	0	0.000		99	1.000	0	0.000	0	0.000
c.738+64G>T	CPP	211	0.544	177	0.456	0.023	60	0.309	91	0.469	43	0.222	0.006†
T=1, G=2	Control	127	0.641	71	0.359		37	0.374	53	0.535	9	0.091
c.1091T>A	CPP	269	0.693	119	0.307	0.031	91	0.469	87	0.449	16	0.082	0.026*
A=1, T=2	Control	154	0.778	44	0.222		60	0.606	34	0.343	5	0.051
c.*120C>G	CPP	362	0.933	26	0.067	0.590	169	0.871	24	0.124	1	0.005	0.661*
C=1, G=2	Control	187	0.944	11	0.056		88	0.889	11	0.111	0	0.000

KISS1R = kisspeptin receptor, SNP = single-nucleotide polymorphism, CPP = central precocious puberty.

^*P value for dominant model; ^†P value for recessive model.