Table 1.
Genes from the C/EBPβ-clustered intestinal-type gastric cancer genes, showing their regulation in both intestinal-type tumors and C/EBPβ KO stomachs. Down-regulated genes in intestinal-type gastric cancer are up-regulated in the C/EBPβ KO stomach
| Gene name | p | Regulated in | FC | p | Regulated in | FC | |
|---|---|---|---|---|---|---|---|
| (int. vs. diff.) | intestinal | (C/EBPβKO vs. WT) | C/EBPβ | ||||
| GC | KO | ||||||
| COL4A6 | Collagen, type IV, alpha 6 | 0.026065 | Down | 2.2 | 0.003434 | Up | 1.8 |
| COX7A1 | Cytochrome c oxidase, | 1.34E−07 | Down | 2.6 | 0.008941 | Up | 2.2 |
| Subunit VIIa 1 | |||||||
| CPE | Carboxypeptidase E | 8.69E−04 | Down | 2 | 8.96E−04 | Up | 1.6 |
| GLI1 | GLI-Kruppel family member GLI1 | 3.39E−05 | Down | 1.9 | 0.001579 | Up | 1.6 |
| HLF | Hepatic leukemia factor | 9.51E−04 | Down | 2.3 | 0.007635 | Up | 1.6 |
| MAMDC2 | MAM domain containing 2 | 1.44E−06 | Down | 6.2 | 0.007404 | Up | 2.3 |
| PDZRN4 | PDZ domain containing RING finger 4 | 0.005077 | Down | 2.9 | 0.007338 | Up | 2 |
| PTCHD1 | Patched domain containing 1 | 0.020572 | Down | 2.1 | 0.00189 | Up | 1.5 |
| PTGER3 | Prostaglandin E receptor 3 | 1.89E−07 | Down | 3.7 | 0.004076 | Up | 1.6 |
| (subtype EP3) | |||||||
| RAI2 | Retinoic acid induced 2 | 6.97E−05 | Down | 2.6 | 0.008717 | Up | 1.6 |
| RUNX1T1 | runt-related transcription factor 1; translocated to, 1 (cyclin D-related) | 1.32E−08 | Down | 5.2 | 0.00741 | Up | 1.5 |
| SPARCL1 | SPARC-like 1 | 9.97E−10 | Down | 2.7 | 0.007544 | Up | 1.5 |
| ZFMP2/FOG2 | Zinc finger protein, multitype 2 | 9.81E−08 | Down | 4.4 | 0.001298 | Up | 1.6 |