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Diverse functions of TG2. TG2 regulates the post-translational modification of several proteins though several activities, including transamidation, GTPase, adhesion/scaffold, kinase, disulfide isomerase, and isopeptidase activities. Some functions of TG2 remain unclear. TG2 exerts different activities depending on the stimuli; these activities lead to several effects, including apoptosis, cell growth, and differentiation
