Table 1.
Organ/system | 0 | 1 | 2 | 3 | 4 |
Liver (bilirubin, mg/dL) | < 1.2 | ≥ 1.2 to ≤ 2 | ≥ 2 to < 6 | ≥ 6 to < 12 | ≥ 12 |
Kidney (creatinine, mg/dL) | < 1.2 | ≥ 1.2 to < 2 | ≥ 2 to < 3.5 | ≥ 3.5 to < 5 or dialysis | ≥ 5 or diálysis |
Cerebral (HE grade) | No HE | I | II | III | IV |
Coagulation (RIN, platelet count) | < 1.1 | ≥ 1.1 to < 1.25 | ≥ 1.25 to < 1.5 | ≥ 1.5 to < 2.5 | ≥ 2.5 or platelet count ≤ 20000 per cubic millimeter |
Circulation (mean arterial pressure, mmHg), inotropic drugs (μg/kg per minute) | ≥ 70 | < 70 | Dopamine ≤ 5 or dobutamine or terlipressin | Dopamine > 5 or E ≤ 0.1 or NE ≤ 0.1 | Dopamine > 15 or E > 0.1 or NE > 0.1 |
Lungs (SpO2/FiO2) | > 512 | > 357 a ≤ 512 | > 214 a ≤ 357 | > 89 to ≤ 214 | ≤ 89 |
The text in bold indicates the diagnostic criteria for organ failure. HE: Hepatic encephalopathy; E: Epinephrine; NE: Norepinephrine; FiO2: Fraction of inspired oxygen; SpO2: Pulse oximetric saturation.