Table 3.

Differences between MIO and OE surgery patients

Variables	No. studies	WMD/OR (95%CI)	P V	P Q	I 2 (%)	P E
Age, years	57 (n = 15790)	−0.343 (−1.200, 0.514)	0.433	<0.05	68.1	0.059
NT	34 (n = 5138)	1.364 (1.042,1.785)	0.024	<0.05	73.0	0.362
Comorbidity
Cardiovascular	16 (n = 10337)	0.913 (0.815,1.022)	0.112	0.030	44.2	0.930
Pulmonary	15 (n = 9779)	0.949 (0.819,1.099)	0.485	0.881	0	0.722
Diabetes	15 (n = 9983)	0.942 (0.798,1.111)	0.476	0.457	0	0.082
Operating time, min	46 (n = 6260)	24.427 (10.912,37.943)	<0.05	<0.05	96.1	0.155
Blood loss, ml	40 (n = 5285)	−196.060 (−255.195,-136.926)	<0.05	<0.05	98.9	0.592
LN harvest	46 (n = 6390)	−1.275 (−5.851,3.301)	0.585	<0.05	99.8	0.786
LOS, day	45 (n = 13899)	−3.660 (−4.891,-2.428)	<0.05	<0.05	86.0	0.175
ICU stay, day	27 (n = 10761)	−1.599 (−2.680, −0.518)	0.004	<0.05	98.2	0.078
Complication
Total complication	35 (n = 5991)	0.700 (0.626,0.781)	<0.05	0.012	38.5	0.178
Pulmonary	50 (n = 14781)	0.527 (0.431, 0.645)	<0.05	<0.05	60.3	<0.05
Circulatory system	36 (n = 12883)	0.770 (0.681,0.872)	<0.05	0.427	2.4	0.386
Digestive system	21 (n = 4081)	1.097 (0.835,1.442)	0.507	0.083	31.7	0.664
AL	50 (n = 7528)	1.023 (0.870,1.202)	0.785	0.304	8.5	0.018
RLNP	37 (n = 5429)	1.108 (0.917,1.339)	0.289	0.089	24.8	0.014
STR	39 (n = 5991)	0.639 (0.522,0.781)	<0.05	0.918	0	0.206
Mortality	38 (n = 14132)	0.668 (0.539,0.827)	<0.05	0.944	0	0.508

NT neoadjuvant therapy, LN lymph node, LOS length of hospital stay, ICU intensive care unit, AL anastomotic leak, RLNP recurrent laryngeal nerve palsy, STR surgical technology-related, Mortality in-hospital/30-day mortality, P _V the P value for pooled, P _Q the P value for Q test, P _E the P value for Egger’s test