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Effect of endotoxin on depressed mood over time in females according to sleep disturbance. Depressed mood was assessed at baseline (T0) and then approximately every hour after injection for the next 6 h (T1–T6). T2 was assessed at 1 h and 40 min after injection; T3 was assessed at 3 h and 30 min after injection; and T4–T6 were assessed hourly after T3. Error bars indicate 95% confidence intervals. *Marginal means adjusted for age, race, BMI, and baseline depressive symptoms.
