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. 2016 Dec 8;7:476. doi: 10.3389/fphar.2016.00476

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Copyright © 2016 Lim, Park, Kim, Kang, Jeong, Youn, Jung, Kim, Kim, Ahn, Kim, Choe, Hong and Um.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Chrysophanic acid suppresses weight gain in HFD-induced obese C57BL/6J mice. (A) Weight changes for 16 weeks, (B) iWAT, eWAT, liver, and BAT tissue weights were measured. (C) Total cholesterol, HDL-cholesterol, LDL-cholesterol, triglyceride, glucose, (D) AST, and AST of blood serum were measured. Data represent means ± SD. ^#p < 0.05 compared with NC, ^∗p < 0.05 compared with HFD. NC, normal control group; HFD, high-fat diet group; HFD + CA, high-fat diet plus CA group (n = 5 per group).