FIGURE 6.

Tissue protein expression of factors associated with stress resistance and cell survival in different regions of the adult human cerebral cortex. The antioxidants catalase and SOD1, the FOXO transcriptional factor FOXO1, the repressor element 1-silencing transcription factor REST, and the master regulator that senses cell nutrient and energy status, mechanistic target of rapamycin mTOR, where all determined with western blot. ^∗p < 0.05; ^∗∗p < 0.01; ^∗∗∗p < 0.001. a, significant differences with respect to entorhinal cortex; b, significant differences with respect to hippocampus. All western blots can be found as Supplementary Figure S1.